New job Associate Scientist, Manufacturing in Missouri
Associate Scientist, Manufacturing
Company : Pfizer
Salary : Details not provided
Location : Missouri
Full Description
Why Patients Need You
Pfizer’s purpose is to deliver breakthroughs that change patients’ lives. Research and Development is at the heart of fulfilling Pfizer’s purpose as we work to translate advanced science and technologies into the therapies and vaccines that matter most. Whether you are in the discovery sciences, ensuring drug safety and efficacy or supporting clinical trials, you will apply cutting edge design and process development capabilities to accelerate and bring the best in class medicines to patients around the world.
What You Will Achieve
The Pilot Plant Associate Scientist will be part of a diverse team of engineers and technicians focused on scale up and optimization of mammalian and microbial fermentation, purification, and conjugation processes enabling efficient production of toxicology and process development supplies to advance Pfizer’s Bio-therapeutics portfolio.
How You Will Achieve It
ROLE RESPONSIBILITIES
- Leading the technical transfer and scale-up of unit operations (upstream, downstream, and conjugation) for non-GMP and GMP production.
- Generation of process batch records, unit operation scheduling, and the purchase, installation, and start-up of new capital equipment.
- Mining and evaluation of process data, modeling, and the generation of reports to support manufacturing campaigns.
- Training of technical personnel for safe and effective operations in the Pilot Plant and conducting process safety assessments.
- Collaboration with other groups within BRD on scale-up experimental studies and technical transfer to clinical manufacturing.
- Contribute to internally reviewed technical reports, and make presentations to other scientific groups and management.
- Responsible for planning and executing operational efficiency improvements for pilot plant work processes, and for determining how advancements in the field and new technology can be integrated into those work processes.
Qualifications
Must-Have
- Bachelor's Degree in Biotechnology, Biochemistry, Biochemical Engineering, Chemical Engineering or equivalent.
- Requires 0-2 years of experience in biologics process development, technology transfer and/or bioprocess manufacturing.
- Must have a basic understanding of the engineering principles of pilot plant operations including microbial and mammalian fermentation, process chromatography, ultrafiltration, and filtration and an understanding of how to scale and control these processes.
- Strong understanding of core principles of process equipment, process control, and engineering concepts.
- Demonstrated capability to work as a team member in a matrix team.
- Ability to work under minimal supervision.
- Organized, self-motivated, and capable of working independently, and in a collaborative environment.
- Strong oral and written communication skills.
- Capable of generating documents utilizing Microsoft Word, Excel, PowerPoint, and Visio.
Nice-to-Have
- Prior experience in a Biological Pilot Plant or GMP Manufacturing setting is desired.
- Strong understanding of core principles of biotechnology, process equipment, process control, engineering concepts, material management and a broad understanding of Pharmaceutical industry practices.
- Previous knowledge of GMP principles and documentation is highly desirable.
PHYSICAL/MENTAL REQUIREMENTS
- Must be able to lift 40 lbs.
Sunshine Act
Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider’s name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.
EEO & Employment Eligibility
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.